Comparative Study of Free Radical Activity in Plasmodium Falciparum and Plasmodium Vivax Malaria Patients
نویسندگان
چکیده
The present study was undertaken to study the free radical activity in malaria patients suffering from plasmodium falciparum (n=14) and plasmodium vivax (n=21) against the healthy control subjects (n=25). Lipid peroxidation was assessed by measuring serum lipid peroxide in both groups of malaria patients by using Malondialdehyde as standard. The serum Ceruloplasmin is also studied along with serum Lipid peroxidation. The level of serum Lipid peroxidation was significantly high (p<0.001) in patients with Plasmodium falciparum malaria as compared to Plasmodium vivax infected patients and healthy controls. Increase in serum Lipid peroxidation may be due to over activity of free radical, which corresponds with severity of tissue damage while increase in serum Ceruloplasmin could be due to acute phase response in malaria. PRAMOD KAMBLE Department of Biochemistry, SDMCMSH, Dharwad, Karnataka, India
منابع مشابه
Molecular Evidence on Changing Pattern of Mixed Plasmodium falciparum and P. vivax Infections during Year-Round Transmission of Malaria in Chahbahar, Iran
Mixed malaria infections, Plasmodium falciparum and P. vivax, are suspected to occur at a greater frequency than is detected by conventional light microscopy. In order to determine the year round pattern of transmission and the frequency of mixed infections in malaria endemic area, we carried out a prospective comparison of diagnosis by conventional light microscopy and nested PCR in Chahbahar ...
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